Secondary induction and the development of tooth nerve supply

K Luukko, K Moe, A Sijaona, T Furmanek… - Annals of Anatomy …, 2008 - Elsevier
… regarding tooth formation and innervation and the putative role of the secondary induction in
… recent data regarding tooth formation and innervation and the emerged putative role of the …

Coordination of tooth morphogenesis and neuronal development through tissue interactions: lessons from mouse models

K Luukko, P Kettunen - Experimental cell research, 2014 - Elsevier
… functions in the mature adult tooth, and that the development of the tooth nerve supply is
tightly, … Tissue recombination experiments showed that the early oral/dental epithelium induces

Mouse rudimentary diastema tooth primordia are devoid of peripheral nerve fibers

S Løes, P Kettunen, I Kvinnsland, K Luukko - Anatomy and embryology, 2002 - Springer
developing tooth, we investigated the distribution of nerve fibers in the buds, and compared
it to the innervation … primary and secondary enamel knots during molar tooth cusp formation. …

… and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfβ1 regulate semaphorin 3a expression in the dental …

P Kettunen, S Løes, T Furmanek, K Fjeld… - 2005 - journals.biologists.com
… Wnt4 induce Sema3aexpression in the presumptive dental … that regulate the development
of tooth nerve supply. It appears … the sites of the developing secondary apical foramina during …

Tissue interactions in the regulation of axon pathfinding during tooth morphogenesis

K Luukko, IH Kvinnsland… - Developmental Dynamics, 2005 - Wiley Online Library
… different stages of tooth innervation development. In addition, … crucial for the establishment
of tooth nerve supply. However, … induces Sema3A expression in the early presumptive dental

Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis

K Luukko, P Suvanto, M Saarma… - Developmental …, 1997 - Wiley Online Library
nervous system that also regulates kidney development. To … lamina, which may represent
the rudiment of secondary tooth … that early dental epithelium has the potential to induce tooth

Integration of tooth morphogenesis and innervation by local tissue interactions, signaling networks, and semaphorin 3A

K Luukko, P Kettunen - Cell Adhesion & Migration, 2016 - Taylor & Francis
… as secondary induction and regulates all aspects of toothdevelopment of the sensory nerve
supply in the tooth germ. Consequently, local inductive signaling within the developing tooth

Deciduous autologous tooth stem cells regenerate dental pulp after implantation into injured teeth

K Xuan, B Li, H Guo, W Sun, X Kou, X He… - Science translational …, 2018 - science.org
… of vital dental pulp, loss of the blood and nerve supply, and … (a procedure that induces tooth
root development and closure of … secondary to trauma, a healthy maxillary deciduous canine …

The application of tissue engineering to regeneration of pulp and dentin in endodontics

M Nakashima, A Akamine - Journal of endodontics, 2005 - Elsevier
… BMP4 from the epithelium induces the mesenchyme to be … of the tooth crown by influencing
the initiation of the secondary knots … The main nerve supply enters the pulp through the apical …

Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation

K Luukko, M Saarma, I Thesleff - Developmental Dynamics: An …, 1998 - Wiley Online Library
nerves during innervation of the cutaneous and oral epithelia as well as dental follicle
surrounding the developing tooth. … After 24 hr culture, dental epithelium had induced a translucent …